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KMID : 0362919960140010033
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Journal of the Korean Society for Therapeutic Radiology and Oncology
1996 Volume.14 No. 1 p.33 ~ p.39
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Radiotherapy Results of Early Uterine Cervix Cancer
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Choi Doo-Ho
Huh Seung-Jae
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Abstract
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Purpose: This study was done to analyze survivals, patterns of failure, and complications of early uterine cervix cancer after curative radiotherapy.
Methods and Materials: Eighty patients with uterine cervix cancer FIGO Stage IB (48 cases) and Stage IIA (32 cases) treated with radiotherapy were analyzed retrospectively. Patients were treated from November 1985 to May 1993, and minimum follow up period was 24 months. and 6 cases were lost to follow up. All of them were treated with external radiotherapy and different fractions of high dose rate intracavitary radiotherapy. Survival rates, failure patterns, complication rates and degrees of severity were analyzed according to several factors.
Results: Overall 5 year survival rate and relapse free survival rate were 72.3%, and 72.8% respectively. Prognostic factors were stage, size, pathology, RT response and there was no significant survival difference among the reasons of radiotherapy choice. There were 19 cases of treatment failure, another 3 cases were not tumor related death, and most of treatment related failure occurred within 24 months. Late complication rate of bladder and rectum were 8.8%, 15% respectively, frequency and severity of complication were correlated with ICR fractionation dose and total dose.
Conclusion: These results showed that survival rates of early stage radiation treated cervix cancer patients were comparable to surgical series, but more aggressive treatment methods needed for stage IIA poor prognostic patients, To decrease late complication, choice of proper ICR dose and meticulous vaginal packing is needed.
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KEYWORD
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Cervix cancer, Radiotherapy, ICR Fractionation, Complication
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